Check whether all the prerequisites are done. The prerequisites can be found here:   https://www.manageengine.com/products/applications_manager/help/prerequisites-for-applications-manager.html#MicrosoftBizTalkMonitoring

If unable to add the Biztalk monitor, follow the below steps:

1. Open powershell in administrator mode in the Applications Manager-installed machine.

2. Go to <Applications Manager Home>\working\conf\application\scripts\powershell directory.

3. Run the below commands by replacing hostname, username and password with that of the reported Biztalk server
   
   

   .\TestConnectivity.ps1 'hostname' 'username' 'password'

4. Copy the output of the above command to a text file.