Check whether all the prerequisites are done. The prerequisites can be found here: https://www.manageengine.com/products/applications_manager/help/prerequisites-for-applications-manager.html#MicrosoftBizTalkMonitoring
Follow the below steps for troubleshooting:
Open powershell in administrator mode in the Applications Manager-installed machine.
Go to <Applications Manager Home>\working\conf\application\scripts\powershell directory.
Copy the output of the above command to a text file.
Reach out to our support team with the text file containing the output to firstname.lastname@example.org along with the latest Support Information File (SIF) from Applications Manager with print all logs enabled for analysis.