I get this message while monitoring web services - "Proxy setting updated. Please restart Applications Manager".

I get this message while monitoring web services - "Proxy setting updated. Please restart Applications Manager".

"Proxy setting updated. Please restart Applications Manager". This message will appear if an external web service (internet) and an internal web service(intranet) are being monitored interchangeably. This is because the proxy setting changes do not take effect dynamically. The internal web service URLs need to be bypassed from the proxy while the external ones need proxy. 
This is just an one time process, so you can configure all your web services and then restart Applications Manager.