Step 1: Please go to Admin --> Delete/Disable Policy --> Disable Policy --> Check Move users to container and choose the OU --> Check Run Custom Script and specify the custom script.
Note: A sample Out-of-Office script is attached to this post.
Step 2: Kindly go to AD Mgmt --> User Management --> Bulk User Modification --> Enable/Disable Users.
Step 3: Please select Disable under Enable/disable the account.
Now, to specify the employees you can,
a. Import a simple CSV file with the sAMAccountName of the users. The users will be matched and displayed. You can then click on Check All and Apply this change.
b. Click on search and it will give you all the users in your domain. You can handpick users and apply this change.
c. If all the users belong to an OU, you can choose the OU on Add OUs and hit Search. All users from that OU would appear. You can then click on Check All and Apply this change.