URL is not opening inside LAN on domain Users PC

URL is not opening inside LAN on domain Users PC

Dear Helpdesk,
I have some problem I have set URL or default URL in self-service portal settings of SDP.From there the URL is opening fine,but it cant be open inside LAN on Domain Users.The Users added already in SDP to manual account rather than in MSP account.Please find attachment also.Please help me out.

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