Tickets in SD+ are getting merged, how to identify them as a separate request?

Tickets in SD+ are getting merged, how to identify them as a separate request?

We are using 2 instances of SD+ for different departments (Dept A and Dept B), when Dept A creates a ticket and assigns it to Dept B, an email to shot to Dept B with the ticket creation details. This email creates a ticket in the SD+ of Dept B.

As the auto response details are in both the SD+'s, tickets are getting created in a looped fashion..

How can we avoid this?

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