Service Desk url cannot be browseable.

I am unable to browse my service desk url. when in morning its working fine. suddenly i am unable to access it. where i have secluded backup running daily but it is scheduled at night, secondly i have schedule a AD sync on daily basis. suddenly i revived error on my Event log that

Category: wrapper
Event 100:
description: configuration error see logs.

kindly update me about the solutions

Note: we are using SDP 7.5 Version.....
SDP manageengine Service is running i have also restarted that but problem is same.

Then i restart my server machine its working fine now. but i am unable to diagnose what the issue is ,

Regards
MAJ