Ok, so here's the scenario.
Ticket 528245 is resolved, and then moves to closed. The following week someone replies to that thread, and it rightfully opens a brand new ticket 533183, instead of reopening the old, now closed ticket.
Here's the rub. The NEW ticket 533183 still references the old one in the subject line, so any replies to that new ticket, since it still has ##RE-528245## in the subject line, continue to open more NEW tickets and create confusion.
Shouldn't the new 533183 ticket have THAT ticket number in the subject line instead?