Is there a way to set a time for a ticket to automatically close?

Is there a way to set a time for a ticket to automatically close?

We have scenarios where the requester will forget about the ticket, and we will send them a reminder reply template urging them to update the ticket. I would like to have a way to set a 48 hour auto close rule/function that will automatically close the request after this 48 hour timer has expired, is this possible?  

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