Disable new request creation through email - Auto Reply?

Disable new request creation through email - Auto Reply?

I have the 'Disable new request creation through email' option set in our Mail Server settings. Users are able to reply via email to open requests fine.

The issue I'm facing is handling closed tickets. I have it set to raise a new request if a user replies to a request that is closed. With the 'Disable new request' setting turned on though, no new request can be created.

Is there a way to send an automatic reply back whenever someone either emails our support address that isn't about an open request (no ##<ticketID>## in the subject line) OR if someone replies to a closed ticket?

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