Design guide and HA DB question.

Design guide and HA DB question.

Does anyone know where i can get a solid design guide?  It seems i need two app servers an two DB servers? 

Is there anything on server builds? 

i have found some simple install guilds but I am looking for something to help me design the app from the ground up.

Also, Do you have to have two DB servers for HA?  or can i point two App servers one Clustered DB instance? 

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