Changing Default location for checking for software

Changing Default location for checking for software

Is there a way to change the default location for checking software from  C:\Program Files (x86) to another location ? 

Since i want to install a software to another directory when trying to deploy a software update I am getting an error message from the log file like this . 

C:\Program Files (x86)\Opera\@+@\opera.exe is not available

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