Change Site with Business Rules

Change Site with Business Rules

Is it possible to create a business rule which will modify the site a ticket is assigned to? As our organization grows we have more users who are working across multiple sites. When these users submit a ticket (via email fetch) the business rules we established to assign a group/technician fail because the ticket is forced into the users site which the necessary group/technician does not have access to.

Any help would be appreciated as it is very time consuming to adjust and assign these tickets manually. Thanks!
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