Can I build a filter with AND and OR at the same time?

Can I build a filter with AND and OR at the same time?

 I'm now analyzing pluses and minuses of a number of support centre software implementations. I see SupportCenter Plus has a good set of functions and looks well which is important too.

However the filter functionality looks not enough. For example, I wonder if I can construct a filter like: "Show me all requests that:

    came from a particular contact
        AND
    are not assigned to a particular set of support representatives
        AND
    are not having "Closed" status
        OR
    marked with text "VERY IMPORTANT FOR ME" in some additional user-defined field"





In other words, can I specify a few conditions that reduce the number of requests shown to me, but at the same time I need to see some requests (that are very important) regardless of whatever other conditions?

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